Hello
Here it is. Hope its not too late.
The Ebola virus has emerged for the first time in 1976, causing several outbreaks in Sudan and Zaire. The brutal nature of the attack and its very important mortality immediately focused the attention of the scientific world. Its degree of contamination is particularly high, which imposed many places, sometimes whole hospitals, in quarantine accompanied by precautions such as during major epidemics plague.
That is why the Ebola virus is considered one of the most dangerous, but this study - as well as the development of a treatment or a vaccine - is hampered by the very small number of highly secure laboratories that may welcome such a study. A modified strain, non-pathogenic, could accelerate research.
Today, the virus is studied only in a handful of high-secured laboratories, very expensive and very rare, because the Equipment, which is available has to go through numerous rules of protection.
The idea of Yoshihiro Kawaoka was to disarm the virus genetically, reducing it to a set of genes that can be experimented with and studied in less restrictive conditions.
A virus amputation of a gene
According to the new study, the system replication of the Ebola virus depends on a single gene, known as VP30. Like most other viruses, Ebola is a genetic indigent. Composed of only 8 genes, it depends entirely on the host cells which provide the equipment necessary for the reproduction. Thus, the VP30 gene uses the cell medium to produce a specific protein that plays a key role in the replication process. Without this gene, it can not develop.
Yoshihiro Kawaoka withdrew this gene of the virus, and found that Ebola became unable to proliferate.
The virologist said that this discovery, the result of several years of hard work, would allow scientists to cultivate the modified virus in all security in cells producing protein VP30. In such an environment, the virus retains its pathogenicity but could not infect healthy cells.
Today many experiments verify his theory.
According to the researchers, except for the fact that it reproduces only in cells that produce the protein VP30, the modified virus is absolutely identical to the pathogenic virus spread in the wild, making it ideal for biological studies necessary for the development of a vaccine against the disease.
Beautyqueen
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